3-Amino-2,6-piperidinedione hydrochloride

English name: 2,6-Dioxopiperidine-3-ammonium chloride

Nickname: 3-aminopiperidine-2,6-dione hydrochloride | 3-aminopiperidine-2,6-dione hydrochloride | 3-amino-2,6-dioxypiperidine hydrochloride | intermediate of lenalidomide | diketone in pomalidomide

CAS NO.24666-56-6

Appearance: Off white powder

Melting point:>208oC (dec.)

Boiling point: 334.5 ° C at 760 mmHg

Flash point: 156.1 ° C

application

3-Amino-2,6-piperidinedione hydrochloride is an important intermediate of lenalidomide. 3-Aminopiperidine-2,6-diketone hydrochloride is a reagent for the preparation of lenalidomide, which can induce CK1 in dChemicalbookel (5q) MDS α Ubiquitination and degradation.

It can also be used to prepare phthalimide conjugates that promote ligand dependent target protein degradation. As an intermediate of anti-tumor drugs.